流體界面的光學微流體檢測器
高精度流量監測和控制
特點
線上流體感測器當前最受歡迎的應用是將該感測器用作微流體氣泡檢測器。氣泡是微流體技術中需要解決的一個大難題，因為它們會誘發流動修改或與實驗相互作用，對樣品造成損害。用戶可以在其設置的任何給定點監測和計算微流體氣泡的通過情況，並相應地實現實驗的自動化。例如，當與OB1 MK3+配對時，有可能增加壓力或切換一個微流控閥，將氣泡引向另一個流體路徑。
優點
- 可靠的非侵入性技術
- 與相機檢查相比更具有成本效益
- 用於真/假邏輯檢測
- 相容性高：管材尺寸範圍廣
- 用於任何地方使用
- 防止氣泡破裂對細胞的損害
- 設置自動化：可以根據氣泡檢測訊號來觸發流體控制操作
線上流體感測器可以直接接在Elveflow的OB1 MK3+上，也可以和感測器讀取裝置一起作為一個獨立的單元使用。
工作原理
線上流體感測的檢測原理是基於對光路的測量，以及當流動介質發生變化時該光路的變化。藉由一束光由一個已知功率的LED發射出來。該光束穿過毛細管和流過的液體。
然後，它被一個NPN矽光電晶體管收集，該電阻將光功率轉換為電訊號。當液體發生變化時，光學指數和光吸收係數也相應發生變化。它引起電功率的變化並允許檢測流體的變化。
optical microfluidic detector of fluid interfaces
HIGHLIGHTS
The most-popular application for the Inline Liquid Sensor is to use the sensor as a microfluidic bubble detector. Bubbles are a big challenge to address in microfluidics, as they can induce flow modifications or interact with the experiment and damage to the sample. Users can monitor and count the passage of microfluidic bubbles at any given point of their setup and automate the experiment accordingly.
For example, when paired with an OB1 MK3+ it is possible to increase the pressure or switch a valve to direct the bubbles into another fluidic path.
BENEFITS
- Reliable non invasive technique
- Cost effective compared to camera check
- Based on true/false logic
- Large compatibility: wide range of tubing size
- Use anywhere in your setup
- Prevents damage in cells with bubble bursts
- Setup automation: it is possible to trigger fluid control operations based on the bubble detection signal
The Inline Fluid Sensor can be plugged directly onto Elveflow’s OB1
Ｍore application information, please refer to the link: https://www.elveflow.com/microfluidic-products/microfluidics-flow-measurement-sensors/microfluidic-bubble-detector-inline-liquid-sensor/#tab-applications
PRINCIPLE OF OPERATION
The Inline Fluid Sensor detection principle is based on the measurement of the optical path and the variation of this path when the flowing medium is changing.
A light beam is emitted by a LED of known power. This light beam goes through the capillary and the fluid flowing through. It is then collected by an NPN silicon phototransistor which converts the light power into an electrical signal. When a the fluid changes, the optical index and the light absorption coefficient change accordingly. It induces a change in the electrical power and allows detection of changes in the fluid.